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ASUS X99-A Motherboard Review @ HiTech Legion
ASUS has presented an excellent X99 based motherboard with the X99-A model, of course it is designed for high end machines since it uses the LGA 2011-3 socket. You also have to consider what you are getting with a Haswell-E chip is pure CPU processing power and for graphics processing you will need a GPU or possibly more than one.
ASUS X99-A Motherboard Review @ HiTech Legion